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Strauss, RW; Scholz, F; Ulbig, MW; Kampik, A; Neubauer, AS.
Artifacts in optical coherence tomography (OCT) imaging of the retina.
Klin Monbl Augenheilkd. 2007; 224(1):47-51 Doi: 10.1055/s-2006-927274
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Strauß Rupert
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Abstract:
Purpose: The purpose of this study was to investigate artifacts of OCT scans and of software analysis for retinal cross-section scans in a specialised retina clinic setting. Methods: A total of 205 vertical cross-hair OCT scans of retinal Stratus OCTs were randomly chosen from the database. All scans had been performed by one experienced technician. There were 75 (37%) normal findings, the remaining scans showed various types of retinal pathology: All scanning artifacts were analysed. Retinal thickness of all scans was measured automatically at the centre of the macula using two different software algorithms: the instrument's built-in "Stratus OCT Viewer V 4.01" and the stand-alone application "Datamedical OCTview V 3.5" (Datamedical Consulting, Hamburg). Errors of the software to correctly identify the retinal surface and the outer highly reflective layer were assigned into three categories: none, minor error (no influence on measurements) and major error. Results: A total of 7.3% of all OCT scans showed scanning artifacts: 5 motion artifacts, 9 scans with low signal intensity and I decentred scan. Scanning artifacts significantly increased the frequency of software errors (p = 0,012). The presence of retinal pathology also increased the number of errors (p = 0,004). Software analysis yielded a total of 20 major and 2 minor errors for the Stratus OCT (overall 10.7%) and 32 major and 64 minor errors for the Datamedical Viewer (p < 0.001). Measurements by Datamedical OCT view were a mean of 57 micron higher due to a different definition of the outer retinal border. Retinal pathologies significantly increased the likelihood of software errors for both algorithms (both p < 0.01), most critical were macular holes and changes in age-related macular degeneration. Conclusion: Scanning artifacts were associated with a significantly higher frequency of software errors. As artifacts of scans and software occur frequently, the interpretation of OCT scans requires special attention to artifacts.
Find related publications in this database (using NLM MeSH Indexing)
Artifacts -
Female -
Humans -
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Male -
Middle Aged -
Reproducibility of Results -
Retina - cytology
Retrospective Studies -
Sensitivity and Specificity -
Software -
Software Validation -
Tomography, Optical Coherence - methods

Find related publications in this database (Keywords)
optical coherence tomography (OCT)
artifact
error
image processing
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