Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Krejs, GJ; Hegglin, J; Säuberli, H; Largiadér, F; Schmid, P; Blum, AL.
Regulation factors of stomach emptying in dogs.
Helv Chir Acta. 1976; 43(1-2):179-182
Web of Science
PubMed
- Führende Autor*innen der Med Uni Graz
- Krejs Günter Josef
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- Abstract:
- Gastric emptying of organic acids was studied in 6 healthy mongrel dogs. After chronic esophagostomies were performed according to the method of Komarov, a total of 340 test meals were instilled. Each test meal consisted of 300 ml of 6 different organic acids with decreasing molecular weight and different concentrations. After the experiments were achieved, each dog underwent a proximal gastric vagotomy according to the method of Amdrup, and experiments with citric acid were repeated. The results may be summarized as follows: multiple stepwise regression analysis of the data is consistent with a model in which gastric emptying of organic acids is regulated by 3 receptors. The receptors respond to concentration of the organic acid, the actual volume, and the type of acid. The volume receptor is located in the corpus of the stomach because the effect of volume accelerates the emptying rate after proximal gastric vagotomy while the effects of concentration and type of acid remain unchanged.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Carboxylic Acids -
- Dogs -
- Gastrointestinal Motility -
- Male -
- Stomach - physiology
- Vagotomy -