Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Krejs, GJ; Lobsiger, MM; Rau, R; Bron, BA; von Büren, US; Peter, P; Brändli, HH; Pirozynski, W; Blum, AL.
Esophageal function in progressive systemic sclerosis.
Acta Hepatogastroenterol (Stuttg). 1976; 23(1):40-46
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- Führende Autor*innen der Med Uni Graz
- Krejs Günter Josef
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- Abstract:
- A prospective study was performed in 13 consecutive patients with systemic progressive sclerosis (PSS). For the diagnosis of impaired esophageal peristalsis cineradiography and manometry are equally useful. Esophageal suction biopsy allows the diagnosis of esophagitis but not of scleroderma. Mild to severe esophageal involvement was observed in 12 patients. In only one patient the esophagus was virtually normal. Dysfunction of the esophageal body may occur early in the course of the disease while incompetence of the lower esophageal sphincter is observed on an average after 7 to 8 years. Both impairment of peristalsis and pressure of the lower esophageal sphincter may lead to delayed esophageal clearance. Relaxation of LES is normal even in the absence of primary peristalsis. Extensive esophageal damage including severe gastroesophageal reflux may be present in the absence of esophageal symptoms.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Biopsy -
- Cineradiography -
- Esophagus - physiopathology Esophagus - radiography
- Female -
- Gastroesophageal Reflux -
- Humans -
- Hydrochloric Acid - diagnostic use
- Male -
- Manometry -
- Middle Aged -
- Scleroderma, Systemic - diagnosis Scleroderma, Systemic - physiopathology
- Time Factors -