Medizinische Universität Graz - Research portal
Selected Publication:
Lang, PF; Weiss, PA; Mayer, HO; Haas, JG; Hönigl, W.
Conservative treatment of ectopic pregnancy with local injection of hyperosmolar glucose solution or prostaglandin-F2 alpha: a prospective randomised study.
LANCET. 1990; 336(8707): 78-81.
Doi: 10.1016/0140-6736(90)91593-Y
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- Co-authors Med Uni Graz
- Haas Josef
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- Abstract:
- In a prospective randomised study, 31 patients with an unruptured tubal pregnancy were treated either with local and systemic prostaglandins or with local instillation of a hyperosmolar glucose solution. Prostaglandin therapy was successful in 13 of 15 patients and glucose therapy in 16 of 16. 9 women treated with prostaglandins had cramping abdominal pains postoperatively. No side-effects were noted in those treated with glucose. At subsequent hysterosalpingography 5 of 6 patients treated with prostaglandins and 7 of 8 treated with glucose had normal tubal configuration and patency. 3 patients treated with glucose later had a normal intrauterine pregnancy, demonstrably through the affected tube in 1 case. These results suggest that local instillation of hyperosmolar glucose solution is an option in the laparoscopic management of unruptured tubal pregnancies.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
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- Dinoprost - administration and dosage Dinoprost - adverse effects Dinoprost - therapeutic use
- Drug Evaluation -
- Female -
- Glucose - administration and dosage Glucose - therapeutic use
- Humans -
- Osmolar Concentration -
- Pregnancy -
- Pregnancy, Ectopic - blood Pregnancy, Ectopic - drug therapy Pregnancy, Ectopic - urine
- Prospective Studies -
- Randomized Controlled Trials as Topic -