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Selected Publication:
Leis, HJ; Malle, E; Hoffmann, O; Klaushofer, K; Fratzl-Zelman, N; Koller, K; Peterlik, M.
Experimental considerations on the measurement of prostaglandins during long-time incubations of neonatal mouse calvaria.
Biochem Biophys Res Commun. 1990; 169(2):545-550
Doi: 10.1016/0006-291X(90)90365-T
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- Leading authors Med Uni Graz
- Leis Hans-Joerg
- Co-authors Med Uni Graz
- Malle Ernst
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- Abstract:
- The influence of experimental conditions during long-time (72 h) incubations of neonatal mouse calvaria on the measurement of prostaglandins was investigated. Incubations of the cultured calvaria were carried out in the presence and absence of stimulating agents of bone resorption, such as thrombin and parathyroid hormone. It was found that during the first 24 h prostaglandin levels, estimated by gas chromatography negative ion chemical ionization mass spectrometry, did not correlate with calcium liberation, but were merely an artefact resulting from surgery by preparing the calvaria.
- Find related publications in this database (using NLM MeSH Indexing)
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- Kinetics - biosynthesis
- Mice - biosynthesis
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- Organ Culture Techniques - biosynthesis
- Parathyroid Hormone - pharmacology
- Prostaglandins - metabolism
- Thrombin - pharmacology