Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Loidolt, D; Vassella, CC; de Weck, AL; Stadler, BM.
The clinical significance of anti-IgE antibodies in the treatment of allergic rhinopathy
LARYNGO RHINO OTOL. 1990; 69: 255-259.
Doi: 10.1055/s-2007-998185
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- Lang-Loidolt Doris
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- Abstract:
- A simple assay, based on monoclonal antibodies, was used to measure "free" anti-IgE antibodies or anti-IgE antibodies in immune complexes of IgE and anti-IgE. No significant correlation was found between serum IgE levels and the concentration of anti-IgE antibodies. Furthermore, patients who were successfully treated by hyposensitization therapy showed only unmeasurable or extremely low anti-IgE antibody levels in their serum. However, patients who were unsuccessfully treated by hyposensitization had elevated anti-IgE serum titers. Thus, determination of anti-IgE antibodies might become a tool for predicting the success of hyposensitization therapy.
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