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Santonja, C; Nieto-González, G; Santos-Briz, Á; Gutiérrez Zufiaurre, Mde L; Cerroni, L; Kutzner, H; Requena, L.
Immunohistochemical detection of parvovirus B19 in "gloves and socks" papular purpuric syndrome: direct evidence for viral endothelial involvement. Report of three cases and review of the literature.
Am J Dermatopathol. 2011; 33(8):790-795
Doi: 10.1097/DAD.0b013e318221bc41
(- Case Report)
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Cerroni Lorenzo
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- Abstract:
- Papular-purpuric "gloves and socks" syndrome is a distinctive dermatosis featuring acral pruritus, edema, and petechiae. It has been attributed in most--but not all--reported cases to Parvovirus B19 infection, on the grounds of serological proof of recent infection or detection of viral DNA by polymerase chain reaction in patient serum or biopsies. We report the immunohistochemical detection of Parvovirus B19 VP2 structural protein in the endothelial lining of dermal blood vessels in 3 examples of Papular-purpuric "gloves and socks" syndrome and review previously described immunohistochemical investigations in cutaneous involvement by this infection.
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Adult -
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Biopsy -
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Capsid Proteins - analysis
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DNA, Viral - isolation & purification
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Edema - virology
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Female -
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Foot Dermatoses - diagnosis
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Hand Dermatoses - diagnosis
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Humans -
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Immunohistochemistry -
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Male -
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Middle Aged -
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Parvoviridae Infections - complications
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Parvovirus B19, Human - chemistry
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Predictive Value of Tests -
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Pruritus - virology
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Purpura - virology
- Find related publications in this database (Keywords)
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gloves and socks popular-purpuric syndrome
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immunohistochemistry
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parvovirus B19