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Santonja, C; Nieto-González, G; Santos-Briz, Á; Gutiérrez Zufiaurre, Mde L; Cerroni, L; Kutzner, H; Requena, L.
Immunohistochemical detection of parvovirus B19 in "gloves and socks" papular purpuric syndrome: direct evidence for viral endothelial involvement. Report of three cases and review of the literature.
Am J Dermatopathol. 2011; 33(8):790-795 Doi: 10.1097/DAD.0b013e318221bc41 (- Case Report)
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Co-authors Med Uni Graz
Cerroni Lorenzo
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Abstract:
Papular-purpuric "gloves and socks" syndrome is a distinctive dermatosis featuring acral pruritus, edema, and petechiae. It has been attributed in most--but not all--reported cases to Parvovirus B19 infection, on the grounds of serological proof of recent infection or detection of viral DNA by polymerase chain reaction in patient serum or biopsies. We report the immunohistochemical detection of Parvovirus B19 VP2 structural protein in the endothelial lining of dermal blood vessels in 3 examples of Papular-purpuric "gloves and socks" syndrome and review previously described immunohistochemical investigations in cutaneous involvement by this infection.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Biopsy -
Capsid Proteins - analysis
DNA, Viral - isolation & purification
Edema - virology
Female -
Foot Dermatoses - diagnosis
Hand Dermatoses - diagnosis
Humans -
Immunohistochemistry -
Male -
Middle Aged -
Parvoviridae Infections - complications
Parvovirus B19, Human - chemistry
Predictive Value of Tests -
Pruritus - virology
Purpura - virology

Find related publications in this database (Keywords)
gloves and socks popular-purpuric syndrome
immunohistochemistry
parvovirus B19
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