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Lindner, E; Weinberger, A; Kirschkamp, T; El-Shabrawi, Y; Barounig, A.
Near-infrared autofluorescence and indocyanine green angiography in central serous chorioretinopathy.
Ophthalmologica. 2012; 227(1):34-38 Doi: 10.1159/000331987
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Leading authors Med Uni Graz
Lindner Ewald
Co-authors Med Uni Graz
El-Shabrawi Yosuf
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Abstract:
To evaluate the diagnostic potential of near-infrared (NIR) autofluorescence (AF) in central serous chorioretinopathy (CSC) and to present a method to analyze NIR-AF findings quantitatively. NIR-AF images, indocyanine green (ICG) angiograms, blue-light autofluorescence (BL-AF) images and fluorescein angiograms were recorded with the use of a confocal scanning laser ophthalmoscope in 19 eyes of 17 patients with CSC. Gray-value ratios were calculated to compare the methods. Using NIR-AF, hypofluorescent spots were observed at the leakage site in 18 of 19 eyes (94.7%). The mean gray-value ratio (±SD) was 0.55 ± 0.22 for the site of the leakage point with NIR-AF and 0.65 ± 0.35 with BL-AF. ICG angiography showed a gray-value ratio of 2.37 ± 2.07. Fluorescein angiography had the best contrast, with a gray-value ratio of 13.44 ± 15.02. NIR-AF demonstrated CSC in 94.7% of the cases. NIR-AF may be a noninvasive alternative to detect CSC. Copyright © 2011 S. Karger AG, Basel.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Central Serous Chorioretinopathy - diagnosis
Coloring Agents -
Female -
Fluorescein Angiography -
Humans -
Indocyanine Green -
Male -
Ophthalmoscopy -

Find related publications in this database (Keywords)
Chronic serous chorioretinopathy
Near-infrared autofluorescence
Indocyanine green angiography
Blue-light autofluorescence
Fluorescein angiography
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