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Lindner, E; Weinberger, A; Kirschkamp, T; El-Shabrawi, Y; Barounig, A.
Near-infrared autofluorescence and indocyanine green angiography in central serous chorioretinopathy.
Ophthalmologica. 2012; 227(1):34-38
Doi: 10.1159/000331987
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
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Lindner Ewald
- Co-authors Med Uni Graz
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El-Shabrawi Yosuf
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- Abstract:
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To evaluate the diagnostic potential of near-infrared (NIR) autofluorescence (AF) in central serous chorioretinopathy (CSC) and to present a method to analyze NIR-AF findings quantitatively.
NIR-AF images, indocyanine green (ICG) angiograms, blue-light autofluorescence (BL-AF) images and fluorescein angiograms were recorded with the use of a confocal scanning laser ophthalmoscope in 19 eyes of 17 patients with CSC. Gray-value ratios were calculated to compare the methods.
Using NIR-AF, hypofluorescent spots were observed at the leakage site in 18 of 19 eyes (94.7%). The mean gray-value ratio (±SD) was 0.55 ± 0.22 for the site of the leakage point with NIR-AF and 0.65 ± 0.35 with BL-AF. ICG angiography showed a gray-value ratio of 2.37 ± 2.07. Fluorescein angiography had the best contrast, with a gray-value ratio of 13.44 ± 15.02.
NIR-AF demonstrated CSC in 94.7% of the cases. NIR-AF may be a noninvasive alternative to detect CSC.
Copyright © 2011 S. Karger AG, Basel.
- Find related publications in this database (using NLM MeSH Indexing)
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Adult -
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Central Serous Chorioretinopathy - diagnosis
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Coloring Agents -
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Female -
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Fluorescein Angiography -
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Humans -
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Indocyanine Green -
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Male -
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Ophthalmoscopy -
- Find related publications in this database (Keywords)
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Chronic serous chorioretinopathy
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Near-infrared autofluorescence
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Indocyanine green angiography
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Blue-light autofluorescence
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Fluorescein angiography