Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Augustin, H; Auprich, M; Mannweiler, S; Pachernegg, O; Al-Ali, BM; Pummer, K.
Prostate cancers detected by saturation repeat biopsy impairs the Partin tables' accuracy to predict final pathological stage.
BJU Int. 2012; 110(3):363-368
Doi: 10.1111/j.1464-410X.2011.10765.x
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- Führende Autor*innen der Med Uni Graz
- Augustin Herbert
- Co-Autor*innen der Med Uni Graz
- Auprich Marco
- Mannweiler Sebastian
- Mohamad Al-Ali Badereddin
- Pachernegg Oliver
- Pummer Karl
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- Abstract:
- OBJECTIVE To analyse the overall accuracy of Partin tables, with special emphasis to potential limitations resulting from differences between prostate cancers detected by different biopsy schedules. PATIENTS AND METHODS Clinical characteristics from 599 patients treated with radical prostatectomy defined the 2007 Partin probabilities of organ confinement (OC), seminal vesicle invasion (SVI) and extracapsular extension (ECE). Prostate cancers were detected by initial biopsy (IBx) with <= 12 cores in 405 patients (67.6%), by conventional repeat biopsy (CRBx) with <= 12 cores in 99 (16.5%) and by saturation repeat biopsy (SRBx) with >= 20 cores in 95 patients (15.9%). The area under the curve (AUC) estimated by the receiver operating characteristic curve, assessed the predictive accuracy of the 2007 Partin tables. RESULTS The Partin tables AUC of the IBx, CRBx and the SRBx groups were 0.730 vs 0.701 vs 0.585 for OC, 0.631 vs 0.689 vs 0.547 for ECE, and 0.775 vs 0.755 vs 0.641 for SVI, respectively. CONCLUSIONS The overall accuracy of the 2007 Partin tables was clearly inferior in patients with prostate cancers detected by SRBx. Prostate cancers detected by SRBx undermine the Partin tables' overall accuracy, and this group of patients may be miscounselled by vague predictions.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Biopsy - methods
- Humans -
- Male -
- Middle Aged -
- Neoplasm Staging -
- Predictive Value of Tests -
- Prostate - pathology
- Prostatectomy - methods
- Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery
- ROC Curve -
- Retreatment -
- Find related publications in this database (Keywords)
- radical prostatectomy
- Partin tables
- saturation biopsy