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Marth, E; Möse, JR; Bencko, V; Tichacek, B; Sixl, W; Köck, M; Sixl-Voigt, B.
Air pollution emissions and changes in lung function
ZBL HYG UMWELTMED. 1989; 188(5): 439-448.
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Leading authors Med Uni Graz
Marth Egon
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Abstract:
Among the environmental hazards in a modern industrial society, air pollutants are of major significance. They can directly affect the cells of the bronchopulmonary system and lead to an irritation of the epithelial and immunocompetent cells. This results in a decreased secretion of immunoglobulin A, and, consequently, a decreased resistance against infections. Thereby pathogens, especially bacteria, may lead to an inflammation of the respiratory tract. Apart from the direct toxic effect of their pollutants, recurrent inflammations eventually lead to small airway obstruction. The spirometric parameters FVC, FEV1 and MEF50 were reduced. IgA concentration in the saliva was determined by means of immunodiffusion and was found to be reduced when compared to a less exposed group. A series of pathogenic germs were isolated from various mucous membranes (conjunctiva, nose/throat). The median immissions for the children examined were 1.345 mg/m3 SO2 and 0.189 mg/m3 HCl.
Find related publications in this database (using NLM MeSH Indexing)
Air Pollutants - adverse effects
Child - adverse effects
Humans - adverse effects
Immunity - drug effects
Immunodiffusion - drug effects
Immunoglobulin A, Secretory - biosynthesis
Lung - drug effects
Lung Diseases, Obstructive - etiology
Male - etiology
Respiratory Tract Infections - etiology
Saliva - immunology

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