Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Zebedin, D; Sorantin, E; Riccabona, M.
Perfusion CT in childhood stroke--initial observations and review of the literature.
Eur J Radiol. 2013; 82(7):1059-1066
Doi: 10.1016/j.ejrad.2011.11.044
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Zebedin Doris
- Co-Autor*innen der Med Uni Graz
- Riccabona Michael
- Sorantin Erich
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- Abstract:
- Introduction: To report the preliminary results of contrast-enhanced perfusion multi-detector CT for diagnoses of perfusion disturbances in children with clinical suspicion of stroke. Patients and methods: Within the last two years emergency perfusion CT was performed in ten children (age: 8-17 years, male: female = 3: 7) for assessment of suspected childhood stroke. These intracranial perfusion CT, intracranial CT-digital subtraction angiography (CT-DSA) and extracranial CT-angiography (CTA) studies were retrospectively reviewed and compared with MRI, follow-up CT, catheter angiography and final clinical diagnosis. The total dose length product (DLP) for the entire examination was recorded. The image quality of perfusion CT-maps, CT-DSA and CTA were evaluated with a subjective three-point scale ranging from very good to non-diagnostic image quality rating perfusion disturbance, intracranial peripheral vessel depiction, and motion-or streak artifacts. Results: In nine of ten children perfusion CT showed no false positive or false negative results. In one of ten children suffering from migraine focal hypo-perfusion was read as perfusion impairment potentially indicating early stroke, but MRI and MRA follow-up were negative. Overall, perfusion-CT with CT-DSA was rated very good in 80% of cases for the detection of perfusion disturbances and vessel anatomy. Conclusions: In comparison to standard CT, contrast-enhanced perfusion CT improves CTs' diagnostic capability in the emergency examination of children with a strong suspicion of ischemic cerebral infarction. Crown Copyright (C) 2011 Published by Elsevier Ireland Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Cerebral Angiography - methods
- Child -
- Contrast Media -
- Female -
- Humans -
- Male -
- Radiographic Image Enhancement - methods
- Reproducibility of Results -
- Sensitivity and Specificity -
- Stroke - radiography
- Tomography, X-Ray Computed - methods
- Find related publications in this database (Keywords)
- Stroke
- Childhood
- (Multi-slice volume) CT