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SHR Neuro Cancer Cardio Lipid Metab Microb

Biccard, BM; Lurati Buse, GA; Burkhart, C; Cuthbertson, BH; Filipovic, M; Gibson, SC; Mahla, E; Leibowitz, DW; Rodseth, RN.
The influence of clinical risk factors on pre-operative B-type natriuretic peptide risk stratification of vascular surgical patients.
Anaesthesia. 2012; 67(1): 55-59. Doi: 10.1111/j.1365-2044.2011.06958.x [OPEN ACCESS]
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Co-authors Med Uni Graz: Mahla Elisabeth
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Abstract:: The role of the revised cardiac risk index in risk stratification has recently been challenged by studies reporting on the superior predictive ability of pre-operative B-type natriuretic peptides. We found that in 850 vascular surgical patients initially risk stratified using B-type natriuretic peptides, reclassification with the number of revised cardiac risk index risk factors worsened risk stratification (pâ<â0.05 for >â0, >â2, >â3 and >â4 risk factors, and pâ=â0.23 for >â1 risk factor). When evaluated with pre-operative B-type natriuretic peptides, none of the revised cardiac risk index risk factors were independent predictors of major adverse cardiac events in vascular patients. The only independent predictor was B-type natriuretic peptide stratification (OR 5.1, 95% CI 1.8-15 for the intermediate class, and OR 25, 95% CI 8.7-70 for the high-risk class). The clinical risk factors in the revised cardiac risk index cannot improve a risk stratification model based on B-type natriuretic peptides. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
Find related publications in this database (using NLM MeSH Indexing): Aged -; Biological Markers -; Female -; Heart Diseases - diagnosis; Humans -; Male -; Middle Aged -; Natriuretic Peptide, Brain - analysis; Odds Ratio -; Postoperative Complications - epidemiology; Preoperative Care -; Reference Standards -; Risk Assessment - methods; Risk Factors -; Vascular Surgical Procedures - adverse effects