Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Deutschmann, HA; Wehrschuetz, M; Augustin, M; Niederkorn, K; Klein, GE.
Long-term follow-up after treatment of intracranial aneurysms with the Pipeline embolization device: results from a single center.
AJNR Am J Neuroradiol. 2012; 33(3):481-486
Doi: 10.3174/ajnr.A2790
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- Leading authors Med Uni Graz
- Deutschmann Hannes
- Co-authors Med Uni Graz
- Klein Guenther
- Niederkorn Kurt
- Wehrschütz Martin
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- Abstract:
- Stent-like, self-expandable devices, the so-called flow diverters, are increasingly used for the treatment of wide-neck cerebral aneurysms. The immediate and short-term results are promising, but no long-term results are available. The purpose of our research was to report the long-term angiographic and cross-sectional imaging results after placement of a PED in 12 patients with wide-neck intracranial aneurysms. Twelve wide-neck or otherwise untreatable cerebral aneurysms in 12 patients were treated with the PED. Angiography was performed at 6 and 24 months after treatment. Additional MR and CT angiograms were acquired. In all patients, angiographic or cross-sectional imaging follow-up of at least 27 months demonstrated complete occlusion of the aneurysms treated with the PED. There were no cases of aneurysm recurrence. Angiography at around 6 months showed complete occlusion in all cases, except 1 that showed complete occlusion at the 29-month follow-up. In 1 patient, a clinically asymptomatic 75% in-stent stenosis was seen on the angiography at 6 months but was resolved completely by balloon dilation. Device placement was successful in all patients. Distal embolization had occurred in 1 patient, but the clot was resolved completely without clinical sequelae. Almost immediate angiographic occlusion was achieved in 2 aneurysms and flow reduction in 10 aneurysms. Treatment of wide-neck intracranial aneurysms by PED placement led to successful and durable occlusion in all cases, without severe complications. Endovascular treatment for in-stent stenosis should be considered cautiously, because the underlying stenosis may be transient and disappear within 12 months after treatment.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Embolization, Therapeutic - instrumentation
- Female -
- Follow-Up Studies -
- Humans -
- Intracranial Aneurysm - diagnosis Intracranial Aneurysm - surgery
- Male -
- Middle Aged -
- Treatment Outcome -