Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
McCloskey, EV; Vasikaran, S; Cooper, C; FRAX(®) Position Development Conference Members.
Official Positions for FRAX® clinical regarding biochemical markers from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®.
J Clin Densitom. 2011; 14(3):220-222
Doi: 10.1016/j.jocd.2011.05.008
Web of Science
PubMed
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- Study Group Mitglieder der Med Uni Graz:
- Dimai Hans Peter
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- Abstract:
- The best indirect evidence that increased bone turnover contributes to fracture risk is the fact that most of the proven therapies for osteoporosis are inhibitors of bone turnover. The evidence base that we can use biochemical markers of bone turnover in the assessment of fracture risk is somewhat less convincing. This relates to natural variability in the markers, problems with the assays, disparity in the statistical analyses of relevant studies and the independence of their contribution to fracture risk. More research is clearly required to address these deficiencies before biochemical markers might contribute a useful independent risk factor for inclusion in FRAX(®).
- Find related publications in this database (using NLM MeSH Indexing)
- Absorptiometry, Photon -
- Biological Markers - blood
- Bone Density -
- Bone Remodeling -
- Diagnosis, Computer-Assisted -
- Femur Neck - radiography
- Fractures, Bone - diagnosis
- Humans -
- Osteoporosis - diagnosis
- Osteoporotic Fractures - diagnosis
- Risk Assessment -
- Risk Factors -
- Find related publications in this database (Keywords)
- Biochemical markers
- FRAX (R)
- fracture risk
- bone turnover