Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Urban, C; Lackner, H; Müller, E; Benesch, M; Strenger, V; Sovinz, P; Schwinger, W.
Stem cell transplantation in 6 children with parvovirus B19- induced severe aplastic anaemia or myelodysplastic syndrome.
Klin Padiatr. 2011; 223(6):332-334
Doi: 10.1055/s-0031-1287839
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Urban Ernst-Christian
- Co-Autor*innen der Med Uni Graz
- Benesch Martin
- Lackner Herwig
- Müller Ewa Christine
- Ritter-Sovinz Petra
- Schwinger Wolfgang
- Strenger Volker
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Parvovirus B19 (PVB19) induced severe aplastic anaemia (SAA) or myelodysplastic syndrome (MDS) is rare, and haematopoietic stem cell transplantation (HSCT) in this condition has not been reported so far. 6 children with SAA (n=4) or MDS (n=2) caused by acute PVB19 infection underwent HSCT under the protection of intravenous immunoglobulines. The 4 children with SAA received matched HLA bone marrow from a sibling (n=3) or peripheral unrelated blood stem cells (n=1). 1 patient had delayed erythrocyte engraftment, whereas 3 patients had an uneventful transplantation course. HSCT in one of the 2 children with MDS was complicated by poor graft function, the other patient engrafted without complications. In conclusion, HSCT in children with PVB19 induced SAA or MDS is feasible, even though some patients may develop delayed engraftment or prolonged poor graft function.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Anemia, Aplastic - therapy
- Bone Marrow Transplantation -
- Child -
- Delayed Graft Function - diagnosis
- Erythema Infectiosum - therapy
- Feasibility Studies -
- Female -
- Hematopoietic Stem Cell Transplantation - methods
- Humans -
- Immunization, Passive -
- Male -
- Myelodysplastic Syndromes - therapy
- Parvovirus B19, Human -
- Retrospective Studies -
- Find related publications in this database (Keywords)
- pediatrics
- haematology
- stem cell transplantation
- parvovirus B19