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Strenger, V; Pfurtscheller, K; Wendelin, G; Aberle, SW; Nacheva, EP; Zöhrer, B; Zenz, W; Nagel, B; Zobel, G; Popow-Kraupp, T.
Differentiating inherited human herpesvirus type 6 genome from primary human herpesvirus type 6 infection by means of dried blood spot from the newborn screening card.
J Pediatr. 2011; 159(5):859-861
Doi: 10.1016/j.jpeds.2011.06.032
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- Führende Autor*innen der Med Uni Graz
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Strenger Volker
- Co-Autor*innen der Med Uni Graz
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Nagel Bert Hermann Philipp
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Pfurtscheller Klaus
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Wendelin Gerald
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Zenz Werner
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Zobel Gerfried
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Zöhrer Bettina
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- Abstract:
- To differentiate active human herpesvirus type 6 (HHV-6) infection from inherited HHV-6 (iHHV-6), we analyzed dried blood spots from archived newborn screening cards in 3 patients with high HHV-6 DNA copy numbers. Two patients were positive for HHV-6 DNA as neonates suggesting iHHV-6. In 1 patient, the absence of HHV-6 DNA excluded iHHV-6.
- Find related publications in this database (using NLM MeSH Indexing)
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Child -
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Child, Preschool -
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DNA, Viral - analysis
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Dried Blood Spot Testing -
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Female -
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Genome, Viral -
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Herpesviridae Infections - congenital Herpesviridae Infections - diagnosis
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Herpesvirus 6, Human - genetics
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Humans -
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In Situ Hybridization, Fluorescence -
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Infant, Newborn -
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Male -
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Neonatal Screening -
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Polymerase Chain Reaction -