Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Pichler, R; Berg, J; Maschek, W; Schimetta, W; Steinwender, C; Hofmann, R; Leisch, F.
Proinflammatory parameters as CRP and IL-6 do not discriminate between post-PCI cardiac patients with and without exercise-induced ischemia as indicated by Tl-201 myocardial scintigraphy.
Cardiovasc Pathol. 2004; 13(6):299-305
Doi: 10.1016/j.carpath.2004.08.001
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Pichler Robert
- Co-authors Med Uni Graz
- Berg Jörg
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- Abstract:
- INTRODUCTION: Atherosclerosis is looked upon as an inflammatory disease. The production of proinflammatory markers may indicate activity in this inflammatory state. METHODS: We prospectively evaluated a range of proinflammatory serum parameters in 136 cardiac patients who had previously undergone percutaneous coronary intervention (PCI). RESULTS: By means of myocardial scintigraphy, an ischemia group (A; n=49) and a group with stable cardiovascular disease without exercise induced ischemia (B; n=87) were distinguished. Risk factors and lipoprotein profile of both groups were comparable. Serum levels of serum C-reactive protein (CRP), IL-6, sTNF-RI, IGF-I, neopterin, serotonin and prolactin did not present any significant difference between the two groups. CONCLUSIONS: We conclude that measurement of these (inflammatory) parameters does not help to delineate post-PCI cardiac patients with and without exercise-induced ischemia.
- Find related publications in this database (using NLM MeSH Indexing)
- Angioplasty, Balloon, Coronary -
- C-Reactive Protein - analysis
- Coronary Artery Disease - blood Coronary Artery Disease - complications Coronary Artery Disease - radionuclide imaging
- Exercise - physiology
- Exercise Test -
- Female -
- Humans -
- Interleukin-6 - blood
- Male -
- Middle Aged -
- Myocardial Ischemia - blood Myocardial Ischemia - etiology Myocardial Ischemia - radionuclide imaging
- Prospective Studies -
- Risk Factors -
- Thallium Radioisotopes - diagnostic use
- Find related publications in this database (Keywords)
- inflammatory markers
- atherosclerosis
- myocardial scintigraphy
- angioplasty