Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Pichler, R; Weiglein, K; Schmekal, B; Sfetsos, K; Maschek, W.
Bone scintigraphy using Tc-99m DPD and F18-FDG in a patient with SAPHO syndrome.
Scand J Rheumatol. 2003; 32(1):58-60
Doi: 10.1080/03009740310000436
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Pichler Robert
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- Abstract:
- Synovitis (inflammatory arthritis), acne (pustulosa), palmoplantar pustulosis, hyperostosis and osteitis (bland osteomyelitis) are symptoms forming the acronym SAPHO. We present the case of a 48-year old man with sterno-costo-clavicular hyperostosis and typical pustulosis palmaris. We performed Tc-99m DPD serial bone scanning to monitor the course of disease and to assess therapeutic efficiency. Control bone scans in 2001 showed minor compromises of the ribs and diminished disease activity on collarbones and the sternum after medication with non-steroidal anti-inflammatory drugs (NSAIDs) and bisphosphonates. F-18 FDG PET presented synovial inflammation in the left sterno-clavicular joint but no relevant tracer uptake on clavicles or breastbones. In case of diagnostic doubts F-18 FDG PET could be recommended in order to discriminate bland osteomyelitis from bacterial osteomyelitis or from bone malignancy when SAPHO-syndrome is assumed.
- Find related publications in this database (using NLM MeSH Indexing)
- Acquired Hyperostosis Syndrome - radionuclide imaging
- Animals -
- Bone Neoplasms - radionuclide imaging
- Bone and Bones - radionuclide imaging
- Diagnosis, Differential -
- Diphosphonates - diagnostic use
- Fluorodeoxyglucose F18 - diagnostic use
- Humans -
- Male -
- Middle Aged -
- Organotechnetium Compounds - diagnostic use
- Osteomyelitis - radionuclide imaging
- Radiopharmaceuticals - diagnostic use
- Tomography, Emission-Computed -
- Find related publications in this database (Keywords)
- SAPHO syndrome
- bone scan
- Tc-99m DPD
- F-18FDG