Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Paar, C; Geit, M; Stekel, H; Berg, J.
Genotypic Prediction of Human Immunodeficiency Virus Type 1 Tropism by Use of Plasma and Peripheral Blood Mononuclear Cells in the Routine Clinical Laboratory
J CLIN MICROBIOL. 2011; 49(7): 2697-2699.
Doi: 10.1128/JCM.00336-11
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- Führende Autor*innen der Med Uni Graz
- Berg Jörg
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- Abstract:
- We developed a sequencing assay for genotypic HIV-1 tropism determination. The assay allows examination of HIV RNA from plasma and HIV DNA from peripheral blood mononuclear cells (PBMC), including PBMC samples from patients with undetectable viral loads. Assessment of 100 pairs of plasma and PBMC samples showed a high concordance of 90%. With the limitations of population-based sequencing, the assay was found to be robust and suitable for the routine clinical laboratory.
- Find related publications in this database (using NLM MeSH Indexing)
- DNA, Viral - genetics
- Genotype -
- HIV Infections - virology
- HIV-1 - genetics HIV-1 - physiology
- Humans -
- Leukocytes, Mononuclear - virology
- Molecular Typing -
- Plasma - virology
- RNA, Viral - genetics
- Sequence Analysis, DNA - methods
- Viral Tropism -
- Virology - methods