Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Friesenbichler, J; Maurer-Ertl, W; Sadoghi, P; Lovse, T; Windhager, R; Leithner, A.
Serum metal ion levels after rotating-hinge knee arthroplasty: comparison between a standard device and a megaprosthesis.
Int Orthop. 2012; 36(3):539-544
Doi: 10.1007/s00264-011-1317-4
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- Führende Autor*innen der Med Uni Graz
- Friesenbichler Jörg
- Maurer-Ertl Werner
- Co-Autor*innen der Med Uni Graz
- Leithner Andreas
- Lovse Thomas
- Sadoghi Patrick
- Windhager Reinhard
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- Abstract:
- Purpose The effects of systemic metal ion exposure in patients with implants made of common prosthetic alloys continue to be a matter of concern. The aim of the study was to determine the measurement values of cobalt (Co), chromium (Cr) and molybdenum (Mo) in serum following rotating-hinge knee arthroplasty. Methods Blood was taken from 25 patients [mean follow-up 35 (range nine to 67) months] treated with megaprostheses (n=17) or standard rotating-hinge devices (n=8) and analysed using electrothermal graphite furnace atomic absorption spectrometry (ET-ASS). Results Determining the concentrations of metal ions following rotating-hinge knee arthroplasty revealed increments for Co and Cr but not Mo. Metal ion release was significantly higher in patients with megaprostheses compared to a standard rotating-hinge knee device (Co p=0,024; Cr p=0.025). Conclusion The authors believe there might be an additional metal ion release from the surface of the prosthesis and not only from the articulating surfaces because, in cases of rotating-hinge knee prosthesis, there is a metal-on-polyethylene articulation and not a direct metal-on-metal junction. Nevertheless, long-term studies are required to determine adverse effects of Co, Cr and Mo following total hip replacement and total knee arthroplasty.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Arthroplasty, Replacement, Knee - adverse effects Arthroplasty, Replacement, Knee - instrumentation Arthroplasty, Replacement, Knee - methods
- Chromium - blood
- Cobalt - blood
- Female -
- Humans -
- Ions -
- Knee Prosthesis -
- Male -
- Metals - blood
- Middle Aged -
- Molybdenum - blood
- Prosthesis Design -
- Prosthesis Failure - adverse effects
- Surface Properties -
- Young Adult -