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Thonhofer, R; Siegel, C; Trummer, M; Langner, C.
Mastocytic enterocolitis as a rare cause of chronic diarrhea in a patient with rheumatoid arthritis.
Wien Klin Wochenschr. 2011; 123(9-10):297-298
Doi: 10.1007/s00508-011-1566-7
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
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Langner Cord
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- Abstract:
- The prevalence of chronic diarrhea within the U.S. population has been reported to be as high as five per cent, and numerous causes have been identified. Especially in patients suffering from rheumatoid arthritis drug therapy should be considered as possible cause. We report a case of chronic diarrhea triggered by mastocytic enterocolitis in a patient suffering from rheumatoid arthritis. Systemic mastocytosis and other causes of chronic diarrhea, especially therapy with methotrexate, were carefully ruled out. Treatment with desloratadin and ranitidine was initiated and led to a rapid and persistent amelioration of clinical symptoms. The diagnosis of mastocytic enterocolitis should be considered in patients with chronic diarrhea and normal clinical, laboratory, as well as endoscopical work-up.
- Find related publications in this database (using NLM MeSH Indexing)
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Anti-Inflammatory Agents, Non-Steroidal - adverse effects
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Anti-Ulcer Agents - therapeutic use
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Arthritis, Rheumatoid - complications
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Biopsy -
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Chronic Disease -
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Diagnosis, Differential -
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Diarrhea - drug therapy
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Drug Therapy, Combination -
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Enterocolitis - complications
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Female -
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Histamine H1 Antagonists, Non-Sedating - therapeutic use
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Humans -
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Immunoglobulin E - blood
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Intestinal Mucosa - drug effects
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Loratadine - analogs & derivatives
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Male -
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Mast Cells - drug effects
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Mastocytosis - complications
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Methotrexate - adverse effects
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Middle Aged -
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Ranitidine - therapeutic use
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Tryptases - analysis
- Find related publications in this database (Keywords)
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Rheumatoid arthritis
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diarrhea
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mastocytic enterocolitis
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mast cells
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methotrexate