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Kerl, H; Wolf, IH; Kerl, K; Cerroni, L; Kutzner, H; Argenyi, ZB.
Ancient melanocytic nevus: a simulator of malignant melanoma.
Am J Dermatopathol. 2011; 33(2):127-130
Doi: 10.1097/IAE.0b013e31817f7b58
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Kerl Helmut
- Co-Autor*innen der Med Uni Graz
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Cerroni Lorenzo
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Wolf Ingrid
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- Abstract:
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Ancient melanocytic nevus (AN) is an unusual but distinctive melanocytic neoplasm within the spectrum of simulators of malignant melanoma. This report describes 13 patients with AN where a long follow-up information was available. Histopathology is characterized by 2 populations of melanocytes, namely, one with large pleomorphic cells and the other with small melanocytes. A few mitotic figures may be present exceptionally. MIB-1 (Ki67) proliferation marker reveals an overall low nuclear labeling index. Additional important findings are stromal degenerative changes. AN must be especially differentiated from dermal melanoma arising in a nevus.
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Adult -
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Aged -
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Diagnosis, Differential -
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Female -
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Humans -
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Ki-67 Antigen - analysis
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Male -
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Melanoma - pathology
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Middle Aged -
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Nevus, Pigmented - pathology
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Skin Neoplasms - pathology
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Young Adult -
- Find related publications in this database (Keywords)
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ancient melanocytic nevus
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pleomorphic melanocytic nevus
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stromal degenerative changes
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dermal melanoma