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Kerl, H; Wolf, IH; Kerl, K; Cerroni, L; Kutzner, H; Argenyi, ZB.
Ancient melanocytic nevus: a simulator of malignant melanoma.
Am J Dermatopathol. 2011; 33(2):127-130 Doi: 10.1097/IAE.0b013e31817f7b58
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Führende Autor*innen der Med Uni Graz
Kerl Helmut
Co-Autor*innen der Med Uni Graz
Cerroni Lorenzo
Wolf Ingrid
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Abstract:
Ancient melanocytic nevus (AN) is an unusual but distinctive melanocytic neoplasm within the spectrum of simulators of malignant melanoma. This report describes 13 patients with AN where a long follow-up information was available. Histopathology is characterized by 2 populations of melanocytes, namely, one with large pleomorphic cells and the other with small melanocytes. A few mitotic figures may be present exceptionally. MIB-1 (Ki67) proliferation marker reveals an overall low nuclear labeling index. Additional important findings are stromal degenerative changes. AN must be especially differentiated from dermal melanoma arising in a nevus.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Diagnosis, Differential -
Female -
Humans -
Ki-67 Antigen - analysis
Male -
Melanoma - pathology
Middle Aged -
Nevus, Pigmented - pathology
Skin Neoplasms - pathology
Young Adult -

Find related publications in this database (Keywords)
ancient melanocytic nevus
pleomorphic melanocytic nevus
stromal degenerative changes
dermal melanoma
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