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Higgins, TS; Hwang, PH; Kingdom, TT; Orlandi, RR; Stammberger, H; Han, JK.
Systematic review of topical vasoconstrictors in endoscopic sinus surgery.
Laryngoscope. 2011; 121(2):422-432
Doi: 10.1002/lary.21286
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
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Stammberger Heinz
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- Abstract:
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The objective of this study is to systematically review the literature and examine the safety for the use of topical vasoconstrictors in endoscopic sinus surgery.
Systematic review clinical trials.
A systematic literature search was performed in MEDLINE, EMBASE, The Cochrane Library, and National Guideline Clearinghouse, and references in the selected articles.
The search criteria captured 42 manuscripts with relevant titles. A systematic review on the topical use of phenylephrine was found; however, no other systematic review, meta-analyses, or clinical guidelines were identified. Six randomized clinical trials or comparative studies, as well as multiple case reports and review articles were also identified. The literature supports the safety of oxymetazoline and epinephrine when used judiciously in carefully selected patients undergoing endoscopic sinonasal surgery; however, topical phenylephrine is not recommended because of its risk profile.
In sinus or nasal surgery, topical vasoconstrictors should be used in a manner that minimizes the risk of cardiovascular morbidity.
Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.
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Administration, Topical -
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Clinical Trials as Topic -
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Endoscopy -
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Humans -
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Otorhinolaryngologic Surgical Procedures - methods
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Paranasal Sinuses - surgery
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Phenylephrine - administration & dosage
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Phenylephrine - adverse effects
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Vasoconstrictor Agents - administration & dosage
- Find related publications in this database (Keywords)
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Complication
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sinus
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vasoconstrictor
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oxymetazoline
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phenylephedrine
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endoscopic surgery
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topical
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nasal
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epinephrine/adrenaline
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xylometazoline
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cocaine
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phenylephrine