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Higgins, TS; Hwang, PH; Kingdom, TT; Orlandi, RR; Stammberger, H; Han, JK.
Systematic review of topical vasoconstrictors in endoscopic sinus surgery.
Laryngoscope. 2011; 121(2):422-432 Doi: 10.1002/lary.21286
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Co-Autor*innen der Med Uni Graz
Stammberger Heinz
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Abstract:
The objective of this study is to systematically review the literature and examine the safety for the use of topical vasoconstrictors in endoscopic sinus surgery. Systematic review clinical trials. A systematic literature search was performed in MEDLINE, EMBASE, The Cochrane Library, and National Guideline Clearinghouse, and references in the selected articles. The search criteria captured 42 manuscripts with relevant titles. A systematic review on the topical use of phenylephrine was found; however, no other systematic review, meta-analyses, or clinical guidelines were identified. Six randomized clinical trials or comparative studies, as well as multiple case reports and review articles were also identified. The literature supports the safety of oxymetazoline and epinephrine when used judiciously in carefully selected patients undergoing endoscopic sinonasal surgery; however, topical phenylephrine is not recommended because of its risk profile. In sinus or nasal surgery, topical vasoconstrictors should be used in a manner that minimizes the risk of cardiovascular morbidity. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.
Find related publications in this database (using NLM MeSH Indexing)
Administration, Topical -
Clinical Trials as Topic -
Endoscopy -
Humans -
Otorhinolaryngologic Surgical Procedures - methods
Paranasal Sinuses - surgery
Phenylephrine - administration & dosage
Phenylephrine - adverse effects
Vasoconstrictor Agents - administration & dosage

Find related publications in this database (Keywords)
Complication
sinus
vasoconstrictor
oxymetazoline
phenylephedrine
endoscopic surgery
topical
nasal
epinephrine/adrenaline
xylometazoline
cocaine
phenylephrine
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