Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Horejsi, R; Kärcher, H; Zwittnig, P; Paletta, B.
Free epinephrine in the ischemic blood of muscle transplants in the rabbit.
BIOMED BIOCHIM ACTA. 1991; 50(8): 993-999.
Web of Science PubMed

 

Führende Autor*innen der Med Uni Graz
Horejsi Renate
Co-Autor*innen der Med Uni Graz
Kärcher Hans
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Abstract:
A stimulated autotransplantation of the rectus femoris muscle in the rabbit was performed by clamping of the blood vessels for 2 h and cutting and suturing of the nerve. Four months after this operation, isometric contractions of the reinnervated muscle were recorded. Comparing controls and postoperation cases, the recovered strength measured about 65%. Due to operation stress, the epinephrine content in plasma was about 420 pg/ml; in plasma of the ischemic muscle it was enhanced to more than 600 pg/ml. During or immediately after ischemia, conjugated epinephrine is assumed to be converted to the free hormone. In systemic blood additionally about 200 pg/ml epinephrine were identified as glucuronides. The activity of adenylate cyclase increased, while the acetylcholine esterase decreased to one-half after nerve cutting.
Find related publications in this database (using NLM MeSH Indexing)
Acetylcholinesterase - metabolism
Adenosine Triphosphatases - metabolism
Animals - metabolism
Catecholamines - blood
Enzyme Activation - blood
Epinephrine - blood
Female - blood
Ischemia - blood
Male - blood
Muscle Contraction - blood
Muscles - blood supply
Rabbits - blood supply
Transplantation, Autologous - blood supply

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