Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Requena, L; Requena, C; Christensen, L; Zimmermann, US; Kutzner, H; Cerroni, L.
Adverse reactions to injectable soft tissue fillers.
J Am Acad Dermatol. 2011; 64(1): 1-34.
Doi: 10.1016/j.jaad.2010.02.064
Web of Science
PubMed
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FullText_MUG
- Co-authors Med Uni Graz
- Cerroni Lorenzo
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- Abstract:
- In recent years, injections with filler agents are often used for wrinkle-treatment and soft tissue augmentation by dermatologists and plastic surgeons. Unfortunately, the ideal filler has not yet been discovered and all of them may induce adverse reactions. Quickly biodegradable or resorbable agents may induce severe complications, but they will normally disappear spontaneously in a few months. Slowly biodegradable or nonresorbable fillers may give rise to severe reactions that show little or no tendency to spontaneous improvement. They may appear several years after the injection, when the patient does not remember which product was injected, and treatment is often insufficient. In this review, we discuss the most commonly used fillers, their most frequent adverse reactions as well as the characteristic histopathologic findings that allow the identification of the injected filler agent. In conclusion, histopathologic study remains as the gold standard technique to identify the responsible filler.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Biocompatible Materials - administration and dosage Biocompatible Materials - adverse effects
- Collagen - adverse effects Collagen - therapeutic use
- Cosmetic Techniques - adverse effects
- Dermatologic Agents - administration and dosage Dermatologic Agents - adverse effects
- Education, Medical, Continuing -
- Esthetics -
- Female -
- Follow-Up Studies -
- Foreign-Body Reaction - etiology Foreign-Body Reaction - physiopathology
- Humans -
- Hyaluronic Acid - administration and dosage Hyaluronic Acid - adverse effects
- Injections, Subcutaneous -
- Male -
- Middle Aged -
- Polymers - administration and dosage Polymers - adverse effects
- Risk Assessment -
- Skin Absorption - drug effects
- Skin Aging - drug effects
- Treatment Outcome -
- Find related publications in this database (Keywords)
- adverse reactions
- bovine collagen
- calcium hydroxylapatite
- dextranomers
- fillers
- histopathology
- hyaluronic acid
- paraffin
- polyacrylamide
- polyalkylimide
- poly-L-lactic acid
- polymethylmethacrylate
- polyvinylhydroxide
- polyvinylpyrrolidone
- silicone