Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Chen, W; Obermayer-Pietsch, B; Hong, JB; Melnik, B; Yamasaki, O; Dessinioti, C; Ju, Q; Liakou, A; Al-Khuzaei, S; Katsambas, A; Ring, J; Zouboulis, C.
Acne-associated syndromes: models for better understanding of acne pathogenesis.
J Eur Acad Dermatol Venereol. 2011; 25(6): 637-646.
Doi: 10.1111/j.1468-3083.2010.03937.x
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Obermayer-Pietsch Barbara
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- Abstract:
- Acne, one of the most common skin disorders, is also a cardinal component of many systemic diseases or syndromes. Their association illustrates the nature of these diseases and is indicative of the pathogenesis of acne. Congenital adrenal hyperplasia (CAH) and seborrhoea-acne-hirsutism-androgenetic alopecia (SAHA) syndrome highlight the role of androgen steroids, while polycystic ovary (PCO) and hyperandrogenism-insulin resistance-acanthosis nigricans (HAIR-AN) syndromes indicate insulin resistance in acne. Apert syndrome with increased fibroblast growth factor receptor 2 (FGFR2) signalling results in follicular hyperkeratinization and sebaceous gland hypertrophy in acne. Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) and pyogenic arthritis-pyoderma gangrenosum-acne (PAPA) syndromes highlight the attributes of inflammation to acne formation. Advances in the understanding of the manifestation and molecular mechanisms of these syndromes will help to clarify acne pathogenesis and develop novel therapeutic modalities.
- Find related publications in this database (using NLM MeSH Indexing)
- Acanthosis Nigricans - complications
- Acne Vulgaris - complications
- Acquired Hyperostosis Syndrome - complications
- Acrocephalosyndactylia - complications
- Adrenal Hyperplasia, Congenital - complications
- Alopecia - complications
- Arthritis, Infectious - complications
- Dermatitis, Seborrheic - complications
- Female -
- Hirsutism - complications
- Humans -
- Hyperandrogenism - complications
- Insulin Resistance -
- Polycystic Ovary Syndrome - complications
- Pyoderma Gangrenosum - complications
- Syndrome -
- Find related publications in this database (Keywords)
- acne
- Apert syndrome
- insulin resistance
- PAPA syndrome
- PCO syndrome
- SAPHO syndrome