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Beran, E; Kapitan, M; Mächler, H; Salaymeh, L; Anelli-Monti, M; Oberwalder, P; Berghold, A; Tscheliessnigg, K.
Accurate preoperative echocardiography has more impact on prediction of long-term mortality than intra-operatively measured flow in coronary bypass grafts.
Eur J Cardiothorac Surg. 2011; 40(1): 245-248. Doi: 10.1016/j.ejcts.2010.11.001 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Beran Elisabeth
Co-Autor*innen der Med Uni Graz
Anelli-Monti Michael
Berghold Andrea
Kapitan Magdalena
Mächler Heinrich
Oberwalder Peter
Salaymeh Luay
Tscheliessnigg Karlheinz
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Abstract:
OBJECTIVE: Our study aimed to analyze the predictive value of intra-operative bypass graft flow measurements for long-term mortality. METHODS: A total of 1593 consecutive coronary artery bypass graft (CABG) patients routinely underwent intra-operative bypass graft flow measurements with the transit-time flow meter (TTFM: Cardiomed(®)). The results of the flow measurements and the demographics were analyzed retrospectively. RESULTS: The mean follow-up was 3.8 years (0.5-8.8 years) with no losses to follow-up. Overall mortality was 10.1%. The preoperative left ventricular ejection fraction (LVEF) (echocardiograph) was the highest independent predictor of long-term survival (hazard ratio 0.97, p = 0.004) in all groups. The univariate analysis for the CABG I group showed that besides LVEF, female gender (hazard ratio 3.6, p = 0.02) was also significant. For the CABG II group, additive EuroSCORE (European System for Cardiac Operative Risk) (ES) (hazard ratio 1.4, p = 0.0001) and age (hazard ratio 1.1, p = 0.001) were significant. In the CABG III group, ES (hazard ratio 1.2, p < 0.0001), age (hazard ratio 1.04, p = 0.001), IMA (hazard ratio 0.5, p < 0.0001) and concomitant aortic valve replacement (AVR) (hazard ratio 2.1, p = 0.03) were significant, in addition to the LVEF. CONCLUSION: With quality-controlled surgeons checked by intra-operative TTFM, accurate quantification of preoperative LVEF significantly predicts long-term outcome. Effective bypass graft flows failed to predict outcome in CABG patients, regardless of the degree of coronary artery disease (CAD) and concomitant AVR. Copyright © 2010 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Age Factors -
Aged -
Aged, 80 and over -
Coronary Artery Bypass - methods
Coronary Circulation - physiology
Coronary Disease - physiopathology
Echocardiography, Doppler - methods
Epidemiologic Methods -
Female -
Humans -
Intraoperative Care - methods
Male -
Middle Aged -
Preoperative Care - methods
Prognosis -
Sex Factors -
Stroke Volume - physiology
Treatment Outcome -
Ventricular Function, Left - physiology

Find related publications in this database (Keywords)
Coronary artery bypass surgery
Transit-time flow measurement
Quality control
Echocardiography
Predicted mortality
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