Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Greimel, E; Nordin, A; Lanceley, A; Creutzberg, CL; van de Poll-Franse, LV; Radisic, VB; Galalae, R; Schmalz, C; Barlow, E; Jensen, PT; Waldenström, AC; Bergmark, K; Chie, WC; Kuljanic, K; Costantini, A; Singer, S; Koensgen, D; Menon, U; Daghofer, F; EORTC Quality of Life Group.
Psychometric validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24).
Eur J Cancer. 2011; 47(2):183-190
Doi: 10.1016/j.ejca.2010.08.014
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Greimel Elfriede Renate
- Co-Autor*innen der Med Uni Graz
- Bjelic-Radisic Vesna
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- Abstract:
- A validation study was conducted to evaluate the psychometric properties of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24). This module was designed to assess disease and treatment specific aspects of the quality of life (QoL) of patients with endometrial cancer. Two hundred and sixty-eight women with endometrial cancer were recruited in different phases of treatment: after pelvic surgery (Group 1); during adjuvant chemotherapy and/or radiotherapy (Group 2); after completion of treatment (Group 3). Patients completed the EORTC QLQ-C30, the endometrial cancer module and a short debriefing questionnaire. Multi-trait scaling analyses confirmed the hypothesised scale structure of the QLQ-EN24. Internal consistency reliability was good with Cronbach's alpha coefficients ranging from 0.74 to 0.86 (lymphoedema 0.80, urological symptoms 0.75, gastrointestinal symptoms 0.74, body image problems 0.86 and sexual/vaginal problems 0.86). Convergent and discriminant validity did not show any scaling errors for the subscales. The QLQ-EN24 module discriminated well between clinically different groups of patients. All items exhibited a high completion rate with less than 2% missing values except for the sexuality items (19%). The validation study supports the reliability, the convergent and divergent validity of the EORTC QLQ-EN24. This newly developed QLQ-EN24 module is a useful instrument for the assessment of the QoL in patients treated for endometrial cancer in clinical trials. Copyright © 2010 Elsevier Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Endometrial Neoplasms - psychology
- Female -
- Humans -
- Karnofsky Performance Status -
- Middle Aged -
- Patient Satisfaction -
- Psychometrics -
- Quality of Life -
- Reproducibility of Results -
- Sensitivity and Specificity -
- Socioeconomic Factors -
- Surveys and Questionnaires - standards
- Find related publications in this database (Keywords)
- Quality of life
- Endometrial cancer
- Questionnaire development
- EORTC
- Psychometric properties