Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Ugurel, S; Hildenbrand, R; Dippel, E; Hochhaus, A; Schadendorf, D.
Dose-dependent severe cutaneous reactions to imatinib.
Br J Cancer. 2003; 88(8):1157-1159
Doi: 10.1038/sj.bjc.6600893
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Ugurel-Becker Selma
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- Abstract:
- The protein kinase inhibitor imatinib has been approved as an efficient anticancer drug with common but mild cutaneous toxicities. We here report on two out of four melanoma patients treated with high-dose imatinib presenting with severe and strongly dose-dependent skin eruptions, suggesting a cutaneous reactivity pattern different from allergic hypersensitivity.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Antineoplastic Agents - toxicity
- Drug Hypersensitivity - pathology
- Female -
- Humans -
- Male -
- Middle Aged -
- Piperazines - toxicity
- Pyrimidines - toxicity
- Skin Diseases - chemically induced Skin Diseases - pathology
- Find related publications in this database (Keywords)
- imatinib
- melanoma
- adverse drug reaction
- c-kit
- mast cells