Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Rödl, S; Marschitz, I; Mache, CJ; Koestenberger, M; Madler, G; Rehak, T; Zobel, G.
First experience with the Prismaflex HF 20 set in four infants.
Int J Artif Organs. 2011; 34(1): 10-15.
Doi: 10.5301/IJAO.2011.6315
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- Führende Autor*innen der Med Uni Graz
- Roedl Siegfried
- Co-Autor*innen der Med Uni Graz
- Koestenberger Martin
- Mache Christoph
- Madler Georg
- Marschitz Ingrid Christine
- Rehak Thomas
- Zobel Gerfried
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- Abstract:
- Purpose: Renal replacement therapy (RRT) in infants is challenging due to a lack of widely available technology that is specific to this patient population. We present our initial experience with the newly developed Prismaflex HF20 (R) disposable set used on the Prismaflex (R) device in infants with renal failure. Patients: Four infants, age 5 to 24 months, were enrolled. Overall 120 treatment sessions were performed over 300 patient-days. Treatment monitoring included patient weight change and fluid balance, treatment efficacy, number of interventions, and alarms. Results: Desired fluid balance according to the prescribed weight loss was achieved in all patients (R(2)=0.86, p<0.0001). Treatment efficacy was monitored by blood urea nitrogen (BUN) and serum creatinine values at the start of RRT (59+/-17 mg/dL and 5.1+/-1.1 mg/dL) and their decrease after 4 hours of RRT (23+/-7 mg/dL and 2.2+/-0.6 mg/dL). Measured urea and creatinine clearances for the HF20 filter were 23+/-7 ml/min and 19+/-4 ml/min, respectively. No complications occurred. Conclusion: This is the first report on the use of the Prismaflex HF20 set in infants. No adverse events were observed, treatments were well tolerated in all patients, and flow rate adaptability to infants' needs was good.
- Find related publications in this database (using NLM MeSH Indexing)
- Biological Markers - blood
- Blood Urea Nitrogen -
- Child, Preschool -
- Creatinine - blood
- Disposable Equipment -
- Equipment Design -
- Hemodiafiltration - instrumentation
- Humans -
- Infant -
- Renal Insufficiency - blood
- Time Factors -
- Treatment Outcome -
- Water-Electrolyte Balance -
- Weight Loss -
- Find related publications in this database (Keywords)
- Hemodiafiltration
- Infants
- End-stage renal disease
- Prismaflex