Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Vermeersch, P; Richter, T; Hauer, AC; Stern, M; Uhlig, HH; Zimmer, KP; Laass, MW; Hoffman, I; Hiele, M; Mothes, T; Bossuyt, X.
Use of likelihood ratios improves clinical interpretation of IgG and IgA anti-DGP antibody testing for celiac disease in adults and children.
Clin Biochem. 2011; 44(2-3):248-250
Doi: 10.1016/j.clinbiochem.2010.09.026
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Hauer Almuthe
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- Abstract:
- To evaluate whether taking into account anti-deamidated gliadin peptide (DGP) antibody concentrations improves clinical interpretation. We calculated likelihood ratios (LR) using data from two previously published studies for assays from EUROIMMUN and INOVA. LRs markedly increased with increasing IgG anti-DGP concentrations. LRs also increased with increasing IgA anti-DGP concentrations, although they were lower than for IgG anti-DGP. Use of LRs for different test result intervals improves clinical interpretation. Copyright © 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Celiac Disease - immunology
- Child -
- Gliadin - immunology
- Humans -
- Immunoglobulin A -
- Immunoglobulin G -
- Transglutaminases -
- Find related publications in this database (Keywords)
- Celiac disease
- Diagnosis
- Deamidated gliadin peptide
- IgG
- IgA
- Sensitivity and specificity