Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Holl, AK; Ille, R; Wilkinson, L; Otti, DV; Hödl, E; Herranhof, B; Reisinger, KM; Müller, N; Painold, A; Holl, EM; Letmaier, M; Bonelli, RM.
Impaired Ideomotor Limb Apraxia in Cortical and Subcortical Dementia: A Comparison of Alzheimer's and Huntington's Disease.
Neurodegener Dis. 2011; 8(4): 208-215.
Doi: 10.1159/000322230
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Holl Anna
- Co-Autor*innen der Med Uni Graz
- Amberger-Otti Daniela
- Holl Etienne
- Huszar-Herranhof Brigitte
- Letmaier Martin
- Painold Annamaria
- Reisinger Karin
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- Abstract:
- Background: Although ideomotor limb apraxia is often considered to occur only in dementia with cortical involvement like Alzheimer's disease (AD), it is also frequently seen in dementia with subcortical degeneration like Huntington's disease (HD). Methods: To assess the occurrence of ideomotor limb apraxia, 46 patients with HD (27 men) and 37 patients with AD (16 men), matched for cognitive performance, were assessed with an apraxia test battery containing tests of the imitation of meaningless hand and finger gestures, the performance of meaningful gestures and of pantomimic movements. Results: There was a high frequency of ideomotor limb apraxia in both AD and HD patients. For the assessment of hands' imitation 13.5% of the AD patients and 41.3% of the HD patients were apraxic, for fingers' imitation 21.6% (AD) and 41.3% (HD) were apraxic, for gestures 27.0% (AD) and 32.6% (HD), and for the assessment of pantomimic movements 24.3% (AD) and 52.2% (HD) showed apraxia. In the AD patients, disease severity was related to the occurrence of apraxia. Conclusions: Ideomotor limb apraxia is a common sign in both groups of patients, occurring in a high percentage. For particular neuropsychological deficits, including ideomotor limb apraxia, a division of dementia in a subcortical and cortical subtype seems to be clinically not meaningful. Copyright (C) 2011 S. Karger AG, Basel
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Alzheimer Disease - complications
- Apraxia, Ideomotor - epidemiology
- Female -
- Humans -
- Huntington Disease - complications
- Male -
- Neuropsychological Tests -
- Find related publications in this database (Keywords)
- Huntington's disease
- Alzheimer's disease
- Apraxia
- Neuropsychological assessment