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Halbmayer, WM; Haushofer, A; Schratzberger, W; Petera, P; Duschet, P; Fischer, M.
Detection of lupus anticoagulants in the routine blood coagulation laboratory exemplified by 36 patients with systemic lupus erythematosus.
Med Klin (Munich). 1993; 88(7):417-422
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Co-authors Med Uni Graz: Haushofer Alexander
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Abstract:: 36 patients suffering from systemic lupus erythematosus (SLE) were subjected to various screening and confirmation tests for the presence of lupus anticoagulants (LA) which are a risk for thrombosis. In five out of the 36 patients (14%) lupus anticoagulants could be found. Five out of the 36 patients (14%) showed increased antiphospholipid antibody (APA) levels whereby only two of these patients were at the same time LA-positive. The specificity, sensitivity and effectiveness of various tests in respect of LA-demonstrability have been assessed and the results taken as the basis for proposal of a largely automated stepwise diagnostic procedure for LA-determination within the routine coagulation laboratory.
Find related publications in this database (using NLM MeSH Indexing): Adult -; Blood Coagulation Tests - economics; Cost-Benefit Analysis -; Female -; Humans -; Lupus Coagulation Inhibitor - analysis; Lupus Erythematosus, Systemic - diagnosis Lupus Erythematosus, Systemic - immunology; Male -; Middle Aged -