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SHR Neuro Cancer Cardio Lipid Metab Microb

Chowers, Y; Sturm, A; Sans, M; Papadakis, K; Gazouli, M; Harbord, M; Jahnel, J; Mantzaris, GJ; Meier, J; Mottet, C; Peyrin-Biroulet, L; Allez, M.
Report of the ECCO workshop on anti-TNF therapy failures in inflammatory bowel diseases: biological roles and effects of TNF and TNF antagonists.
J Crohns Colitis. 2010; 4(4):367-376 Doi: 10.1016/j.crohns.2010.05.011 [OPEN ACCESS]
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Co-authors Med Uni Graz
Jahnel Jörg
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Abstract:
This second section of the first ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases addresses the biological roles of TNFα and the effects and mechanisms of action of TNFα antagonists. Mechanisms underlying their failure, including induction of TNF-independent inflammatory pathways and phenomena of paradoxical inflammation are discussed. Copyright © 2010 European Crohn's and Colitis Organisation. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Animals -
Antibodies, Monoclonal - pharmacology
Antibodies, Monoclonal - therapeutic use
Colitis, Ulcerative - drug therapy
Colitis, Ulcerative - immunology
Colitis, Ulcerative - physiopathology
Crohn Disease - drug therapy
Crohn Disease - immunology
Crohn Disease - physiopathology
Humans -
Inflammatory Bowel Diseases - drug therapy
Inflammatory Bowel Diseases - immunology
Inflammatory Bowel Diseases - physiopathology
Interferon-alpha - physiology
Interleukin-17 - physiology
Interleukin-23 - physiology
Mice -
NK Cell Lectin-Like Receptor Subfamily K - physiology
Treatment Failure -
Tumor Necrosis Factor-alpha - antagonists & inhibitors
Tumor Necrosis Factor-alpha - physiology

Find related publications in this database (Keywords)
Inflammatory bowel diseases
Crohn's disease
Ulcerative colitis
TNF alpha
Anti-TNF therapy
Paradoxical inflammation
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