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Selected Publication:
EGGENSTEIN, C; BORCHARDT, M; DUMSCHAT, C; GRUNDIG, B; CAMMANN, K; SPENER, F; KNOLL, M.
POTENTIOMETRIC BIOSENSOR IN DOUBLE MATRIX MEMBRANE TECHNOLOGY
BIOSENS BIOELECTRON. 1995; 10(6-7): 595-600.
Doi: 10.1016/0956-5663(95)96935-R
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- Co-authors Med Uni Graz
- Spener Friedrich
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- Abstract:
- A throw-away urea sensor is described. A pH-sensitive disposable sensor constructed using double matrix membrane technology was used as a transducer. Double matrix membrane technology describes a process where an ion-sensitive polymer matrix membrane is formed in the presence of an additional inert matrix for to improve the reproducibility of sensor production. In this case one-side silver-coated filter paper was used as the inert matrix which was encapsulated by a heat sealing film. A pH-sensitive membrane was casted into this filter paper and on the surface of this membrane a urease containing layer was deposited. The sensor responded to between 10(-2) mol/l and 10(-4) mol/l urea, the response slope was 32.7 mV/decade. The concentration range in which the sensor responds is important for clinical analysis. The main advantages of this pH-based urea electrode include miniature size as well as simple and low cost fabrication in a batch process.
- Find related publications in this database (Keywords)
- POTENTIOMETRIC BIOSENSOR
- UREA SENSOR
- DISPOSABLE BIOSENSOR