Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Owada, Y; Abdelwahab, SA; Suzuki, R; Iwasa, H; Sakagami, H; Spener, F; Kondo, H.
Localization of epidermal-type fatty acid binding protein in alveolar macrophages and some alveolar type II epithelial cells in mouse lung.
Histochem J. 2001; 33(8):453-457
Doi: 10.1023/A:1014420330284
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- Co-Autor*innen der Med Uni Graz
- Spener Friedrich
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- Abstract:
- Almost all alveolar macrophages in the mouse lung were strongly immunoreactive for epidermal-type fatty acid binding protein. At the electron microscope level, the immunoreactive material was localized diffusely in the cytoplasm but not within the nucleus. A certain number of alveolar type II epithelial cells were also immunoreactive for the protein with variable immunointensity, while a substantial number of the type II cells were immunonegative. No immunoreactive interstitial fibroblasts were encountered. Based on the present findings, possible roles of epidermal-type fatty acid binding protein in the host-defence mechanism played by alveolar macrophages are suggested.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Blotting, Northern -
- Carrier Proteins - genetics Carrier Proteins - metabolism
- Epidermis - chemistry
- Fatty Acid-Binding Proteins -
- Female -
- Lung - chemistry
- Macrophages, Alveolar - metabolism Macrophages, Alveolar - ultrastructure
- Male -
- Mice -
- Mice, Inbred BALB C -
- Microscopy, Immunoelectron -
- Neoplasm Proteins -
- Nerve Tissue Proteins -
- Pulmonary Alveoli - metabolism Pulmonary Alveoli - ultrastructure
- RNA, Messenger - metabolism