Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Krause, R; Salzer, HF; Honigl, M; Valentin, T; Auner, HW; Zollner-Schwetz, I.
Comparison of fluorescence in situ hybridisation using peptide nucleic acid probes, Gram stain/acridine orange leukocyte cytospin and differential time to positivity methods for detection of catheter-related bloodstream infection in patients after haematopoietic stem cell transplantation
CLIN MICROBIOL INFECT. 2010; 16(10): 1591-1593.
Doi: 10.1111/j.1469-0691.2010.03154.x
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- Führende Autor*innen der Med Uni Graz
- Krause Robert
- Co-Autor*innen der Med Uni Graz
- Hönigl Martin
- Salzer Helmut J. F.
- Valentin Thomas
- Zollner-Schwetz Ines
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- Abstract:
- In 46 febrile neutropenic patients who had undergone haematopoietic stem cell transplantation, the fluorescence in situ hybridisation using peptide nucleic acid probes (PNA FISH), Gram stain/acridine orange leukocyte cytospin (Gram/AOLC), and differential time to positivity (DTP) methods were performed for detection of catheter-related bloodstream infections (CRBSIs). As compared with the DTP method (which detected 11 patients with CRBSI), the PNA FISH and the Gram/AOLC methods detected ten of 11 CRBSI patients, resulting in a sensitivity, specificity, negative predictive value and positive predictive value of 91%, 100%, 97% and 100%, respectively, for the PNA FISH method as well as for the Gram/AOLC method.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Catheter-Related Infections - diagnosis
- Female -
- Fever of Unknown Origin - diagnosis
- Humans -
- Male -
- Microbiological Techniques - methods
- Middle Aged -
- Predictive Value of Tests -
- Sensitivity and Specificity -
- Stem Cell Transplantation - adverse effects