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Klemke, CD; Goerdt, S; Schrama, D; Becker, JC.
New insights into the molecular biology and targeted therapy of cutaneous T-cell lymphomas.
J Dtsch Dermatol Ges. 2006; 4(5):395-406 Doi: 10.1111/j.1610-0387.2006.05982.x
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Co-Autor*innen der Med Uni Graz
Becker Jürgen Christian
Schrama David
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Abstract:
Cutaneous T-cell lymphoma is an extra-nodal non-Hodgkin lymphoma of mature T cells. These tumor cells home to and persist in the skin,producing a broad spectrum of clinical entities. Recent results of basic research on tumor biology and tumor immunology as well as molecular genetics of cutaneous T-cell lymphoma have fostered the development of new therapeutic approaches. Several clinical trials testing these targeted therapies have shown encouraging results. This article provides an overview of recent research developments and therapeutic strategies for cutaneous T-cell lymphoma.
Find related publications in this database (using NLM MeSH Indexing)
Animals -
Antineoplastic Agents - administration and dosage
Drug Delivery Systems - methods Drug Delivery Systems - trends
Gene Targeting - methods Gene Targeting - trends
Gene Therapy - methods Gene Therapy - trends
Humans -
Lymphoma, T-Cell - drug therapy Lymphoma, T-Cell - physiopathology
Molecular Biology - trends
Skin Neoplasms - drug therapy Skin Neoplasms - physiopathology

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