Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Bruce, SJ; Breton, I; Decombaz, J; Boesch, C; Scheurer, E; Montoliu, I; Rezzi, S; Kochhar, S; Guy, PA.
A plasma global metabolic profiling approach applied to an exercise study monitoring the effects of glucose, galactose and fructose drinks during post-exercise recovery.
J Chromatogr B Analyt Technol Biomed Life Sci. 2010; 878(29):3015-3023
Doi: 10.1016/j.jchromb.2010.09.004
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Scheurer Eva
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- A global metabolic profiling methodology based on gas chromatography coupled to time-of-flight mass spectrometry (GC-TOFMS) for human plasma was applied to a human exercise study focused on the effects of beverages containing glucose, galactose, or fructose taken after exercise and throughout a recovery period of 6 h and 45 min. One group of 10 well trained male cyclists performed 3 experimental sessions on separate days (randomized, single center). After performing a standardized depletion protocol on a bicycle, subjects consumed one of three different beverages: maltodextrin (MD)+glucose (2:1 ratio), MD+galactose (2:1), and MD+fructose (2:1), consumed at an average of ∼1.25 g of carbohydrate (CHO) ingested per minute. Blood was taken straight after exercise and every 45 min within the recovery phase. With the resulting blood plasma, insulin, free fatty acid (FFA) profile, glucose, and GC-TOFMS global metabolic profiling measurements were performed. The resulting profiling data was able to match the results obtained from the other clinical measurements with the addition of being able to follow many different metabolites throughout the recovery period. The data quality was assessed, with all the labelled internal standards yielding values of <15% CV for all samples (n=335), apart from the labelled sucrose which gave a value of 15.19%. Differences between recovery treatments including the appearance of galactonic acid from the galactose based beverage were also highlighted.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Beverages - analysis
- Blood Glucose - analysis
- Exercise -
- Fatty Acids - blood
- Fructose - blood
- Galactose - blood
- Glucose - metabolism
- Humans -
- Insulin - blood
- Male -
- Metabolome -
- Young Adult -
- Find related publications in this database (Keywords)
- GC TOF
- Metabolomics
- Post exercise recovery
- Galactonic acid
- Glucose
- Galactose
- Fructose
- Human nutrition
- Sports drink