Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Feichtinger, M; Pau, M; Zemann, W; Aigner, RM; Kärcher, H.
Intraoperative control of resection margins in advanced head and neck cancer using a 3D-navigation system based on PET/CT image fusion.
J Craniomaxillofac Surg. 2010; 38(8): 589-594.
Doi: 10.1016/j.jcms.2010.02.004
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Feichtinger Matthias
- Pau Mauro
- Co-Autor*innen der Med Uni Graz
- Aigner Reingard
- Kärcher Hans
- Zemann Wolfgang
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- Abstract:
- Local recurrent of disease in advanced carcinomas of the head and neck is strongly correlated with the presence of positive or close resection margins after operative treatment. The purpose of this study is to present a new method of assessing resection margins intraoperatively using image-guided surgery based on positron emission tomography/computed tomography (PET/CT) image fusion. In 6 patients who underwent surgical treatment of head and neck stage for T4a-T4b carcinomas PET/CT image fusion was done on the workstation of a 3D-navigation system. Intraoperative image-guided navigation of the defect following surgical ablation of the tumour was performed in every patient. Intraoperative navigation of the ablative defect showed an unsafe resection margin in 4 patients. In three of these patients additional image-guided resection allowed local control of the tumour to be achieved. In one patient additional resection was not possible due to skull base invasion. The histopathological exam of the four tumour specimens confirmed positive or close resection margins. The current results suggest that intraoperative control of the surgical margins using a 3D-navigation system based on PET/CT image fusion can be a useful tool to assess and improve local control in advanced cancer of the head and neck.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Carcinoma, Adenoid Cystic - mortality Carcinoma, Adenoid Cystic - pathology Carcinoma, Adenoid Cystic - radiography Carcinoma, Adenoid Cystic - surgery
- Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiography Carcinoma, Squamous Cell - surgery
- Disease-Free Survival -
- Female -
- Head and Neck Neoplasms - mortality Head and Neck Neoplasms - pathology Head and Neck Neoplasms - radiography Head and Neck Neoplasms - surgery
- Humans -
- Image Processing, Computer-Assisted -
- Imaging, Three-Dimensional - instrumentation Imaging, Three-Dimensional - methods
- Intraoperative Care -
- Male -
- Middle Aged -
- Models, Anatomic -
- Positron-Emission Tomography -
- Surgery, Computer-Assisted - methods
- Tomography, X-Ray Computed -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- PET/CT
- image-guided surgery
- resection margins
- advanced head and neck cancer