Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Dalpiaz, O; Neururer, R; Bartsch, G; Peschel, R.
Haemostatic sealants in nephron-sparing surgery: what surgeons need to know.
BJU Int. 2008; 102(11): 1502-1508.
Doi: 10.1111/j.1464-410X.2008.08035.x
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Dalpiaz Orietta
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Surgical haemostatic agents have been increasingly applied for the control of bleeding, and have excellent potential in laparoscopy. Several factors are important when evaluating the use of sealants. We present a brief overview of the history, composition and mechanism of action of sealants, together with a report on experimental studies and clinical experience with haemostatic sealants. We searched for reports on haemostatic agents and their use in renal parenchymal haemostasis; 15 animal models studies and 11 papers on clinical experience were included. The development of haemostatic agents and instruments is allowing the wider diffusion of challenging procedures. Several experimental animal studies have shown the efficacy and safety of sealants for haemostasis during nephron-sparing surgery. Clinical studies confirm the effectiveness of synthetic or fibrin glue, in particular during laparoscopic surgery. Sealants are effective and safe topical agents to control bleeding during nephron-sparing surgery. They should not be viewed as an alternative, but as complementary agents to be used to improve surgical outcomes. Further prospective studies are necessary to validate their role in relation to other haemostatic support techniques.
- Find related publications in this database (using NLM MeSH Indexing)
- Blood Loss, Surgical - prevention and control
- Fibrin Tissue Adhesive - adverse effects Fibrin Tissue Adhesive - pharmacology
- Hemostatics - chemistry Hemostatics - pharmacology
- Humans -
- Laparoscopy -
- Nephrectomy - adverse effects Nephrectomy - methods
- Nephrons - surgery
- Thrombin - pharmacology
- Tissue Adhesives - adverse effects Tissue Adhesives - chemistry Tissue Adhesives - pharmacology
- Find related publications in this database (Keywords)
- fibrin sealants
- haemostasis
- laparoscopy
- nephron sparing surgery
- synthetic
- glue