Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Dornbusch, HJ; Groll, A; Walsh, TJ.
Diagnosis of invasive fungal infections in immunocompromised children.
CLIN MICROBIOL INFECT. 2010; 16(9): 1328-1334.
Doi: 10.1111/j.1469-0691.2010.03336.x
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- Führende Autor*innen der Med Uni Graz
- Dornbusch Hans Jürgen
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- Abstract:
- Early recognition and rapid initiation of effective treatment is a prerequisite for successful management of children with invasive fungal infections. The increasing diversity of fungal pathogens in high-risk patients, the differences in the antifungal spectra of available agents and the increasing rates of resistance call for identification of the infecting isolate at the species level and for information on drug resistance, in order to provide state-of-the-art patient care. Microscopy and culture of appropriate specimens remain the reference standard for mycological diagnosis, despite difficulties in obtaining appropriate and/or sufficient specimens, long durations of culture and false-negative results. Modern imaging studies and detection of circulating fungal cell wall components and DNA in blood and other body fluids or in affected tissues may improve the laboratory diagnosis of invasive mycoses.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Antifungal Agents - pharmacology
- Child -
- Child, Preschool -
- Fever of Unknown Origin - diagnosis
- Fungi - drug effects
- Humans -
- Immunocompromised Host -
- Infant -
- Infant, Newborn -
- Microbial Sensitivity Tests -
- Mycoses - diagnosis
- Opportunistic Infections - diagnosis
- Find related publications in this database (Keywords)
- Children
- diagnosis
- fungal infections
- imaging
- non-culture methods
- review