Medizinische Universität Graz - Research portal
Selected Publication:
Beham-Schmid, C; Beham, A; Jakse, R; Auböck, L; Höfler, G.
Extranodal follicular dendritic cell tumour of the nasopharynx.
Virchows Arch. 1998; 432(3):293-298
Doi: 10.1007%2Fs004280050168
(- Case Report)
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- Leading authors Med Uni Graz
- Beham-Schmid Christine
- Co-authors Med Uni Graz
- Beham Alfred
- Höfler Gerald
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- Abstract:
- We report the first case of an extranodal follicular dendritic cell (FDC) tumour localized in the nasopharynx of a 44-year-old male patient. The tumour cells were characterized immunohistochemically by strong expression of CD21, HLA-DR and vimentin and focal expression of CD68 and cytokeratin. Electron microscopic examination revealed desmosomal cell junctions between adjacent cell processes. Molecular genetic analysis using polymerase chain reaction (PCR) showed germline configuration of immunoglobulin and T-cell receptor genes. Epstein-Barr virus (EBV) genomes were detectable by PCR. After complete surgical tumour removal and radiotherapy the patient is disease-free 20 months after the initial diagnosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Dendritic Cells - pathology
- Gene Rearrangement - pathology
- Humans - pathology
- Immunohistochemistry - pathology
- Lymph Nodes - pathology
- Male - pathology
- Microscopy, Electron - pathology
- Nasopharyngeal Neoplasms - genetics
- Find related publications in this database (Keywords)
- Follicular Dendritic Cell Tumor
- Nasopharynx
- Immunohistochemistry
- Electron Microscopy
- PCR