Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Porta, S; Korisek, G; Machan, B; Gaggi, H; Desch, G; Porta, J; Schappacher, G; Kisters, K.
Changes in electrolyte and metabolic interactions below the hypomagnesemic threshold in Type 2 diabetics
TRACE ELEM ELECTROLYTES. 2010; 27(3): 119-124.
Doi: 10.5414/TEP27119
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Porta Sepp
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- Abstract:
- Out of 100 mu l of capillary blood of 72 diabetic patients, whose daily glucose profile was routinely checked at 9:00 a.m., 12:00 a.m. and 2:00 p.m., ionized Mg and Ca, pCO(2) baseexcess, pH and lactate were simultaneously determined. It turned out that Mg and Ca values as well as baseexcess and pCO(2) values were very low. Correlative analyzes with Mg and the other parameters showed a marked alteration in proportionalities below the hypomagnesemic threshold of 0.45 mmol/l. Below that concentration, the importance of Mg in the Ca/Mg quotient diminished, there was no more significant negative Mg/glucose correlation as has been the case in patients above the threshold and a negative pCO(2)/pH correlation was much clearer than in the patients above the hypomagnesemic threshold. We conclude that low magnesium concentrations in diabetics which are uncommonly frequent (about 36% of our patients including 0.45 mmol/l and 25% lower than 0.45 mmol/l) should be given more attention, because those changes in metabolic interdependencies below the 0.45 mmol/l mark are not inconsistent with exhaustive processes.
- Find related publications in this database (Keywords)
- magnesium
- calcium
- Ca/Mg quotient
- glucose profile
- baseexcess
- pCO(2)
- hypomagnesemic threshold