Medizinische Universität Graz - Research portal
Selected Publication:
Benzer, A; Ofner, D; Tötsch, M; Klima, G.
Early diagnosis of fat embolism syndrome by automated image analysis of alveolar macrophages.
J Clin Monit. 1994; 10(3):213-215
Doi: 10.1007/BF02908864
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- Tötsch Martin
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- To evaluate the value of automated semiquantitative analysis of fat within alveolar macrophages as an early diagnostic tool for fat embolism syndrome (FES), we investigated 3 patients with respiratory failure following long-bone fractures. The mean area of fat droplets per alveolar macrophage was determined in pixels and, additionally, the percentage of the evaluated areas was calculated. In 2 patients, the diagnosis of FES could be established as early as 24 hr after trauma. Both patients showed an increase in the area of fat per alveolar macrophage (pixels: 851, 1069) as well as in the percentage of fat area per alveolar macrophage area (40.04%, 52.73%), whereas the analysis of the bronchoalveolar lavage (BAL) specimens of a third patient, who later recovered without appearance of clinical signs of FES, revealed only minimal fat content (pixels: 82; 3.82%). Automated semiquantitative analysis of fat within alveolar macrophages may be helpful in the early diagnosis of FES.
- Find related publications in this database (using NLM MeSH Indexing)
- Embolism, Fat - diagnosis Embolism, Fat - etiology
- Fractures, Bone - complications
- Humans -
- Image Processing, Computer-Assisted -
- Lipids - analysis
- Macrophages, Alveolar - chemistry Macrophages, Alveolar - pathology
- Find related publications in this database (Keywords)
- FAT EMBOLISM SYNDROME (FES)
- TRAUMA
- DIAGNOSIS