Medizinische Universität Graz - Research portal
Selected Publication:
Ladurner, D; Tötsch, M; Luze, T; Bangerl, I; Sandbichler, P; Schmid, KW.
Malignant hemangioendothelioma of the thyroid gland. Pathology, clinical aspects and prognosis
Wien Klin Wochenschr. 1990; 102(9): 256-259.
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- Co-authors Med Uni Graz
- Tötsch Martin
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- Abstract:
- Malignant hemangioendothelioma (MHE) of the thyroid still constitutes a relatively important part of our surgical material, with 23 MHE (2.0%) among 1153 primary thyroid tumors diagnosed between 1952 and 1987 (biopsy material of the Innsbruck Pathology Institute). 18 of these cases were investigated immunohistochemically; in 14 cases the data on clinical findings and follow-up were complete. Immunohistochemical results confirm the endothelial origin of this tumor and allow MHE to be definitively distinguished from anaplastic carcinomas. Follow-up and prognosis are determined by the aggressive nature of local tumor spread. 13 patients died after a median survival period of 2.4 months (R: 1.2-9.4). Only one patient has remained alive since over 4 1/2 years now. An improvement of the hitherto dismal prognosis is thought to depend on early tumor diagnosis and an ameliorated combined modality treatment.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Female -
- Hemangioendothelioma - mortality Hemangioendothelioma - pathology Hemangioendothelioma - surgery
- Humans -
- Life Tables -
- Male -
- Middle Aged -
- Neoplasm Staging -
- Postoperative Complications - mortality
- Survival Rate -
- Thyroid Gland - pathology
- Thyroid Neoplasms - mortality Thyroid Neoplasms - pathology Thyroid Neoplasms - surgery
- Thyroidectomy -
- Tumor Markers, Biological - analysis