Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ikeoka, D; Mader, JK; Pieber, TR.
Adipose tissue, inflammation and cardiovascular disease.
Rev Assoc Med Bras. 2010; 56(1): 116-121.
Doi: 10.1590/S0104-42302010000100026
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- Führende Autor*innen der Med Uni Graz
- Ikeoka Dimas
- Co-Autor*innen der Med Uni Graz
- Mader Julia
- Pieber Thomas
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- Abstract:
- Obesity has become a very frequent condition with important consequences for the health of affected individuals. Current evidence shows that the excess of adipose tissue as observed in obesity is responsible for secreting inflammatory mediators in a deregulated manner, thus inducing a chronic state of systemic low-grade inflammation that underlies the metabolic and cardiovascular outcomes in these populations. This article reviews the state of the art regarding mediators produced in the adipose tissue, their roles in the pathophysiology of obesity-associated insulin resistance and diabetes, and finally, tries to build a bridge between these mechanistically oriented insights and clinical practice.
- Find related publications in this database (using NLM MeSH Indexing)
- Adipose Tissue - metabolism
- Humans -
- Inflammation - metabolism
- Inflammation Mediators - metabolism
- Insulin Resistance -
- Obesity - metabolism
- Find related publications in this database (Keywords)
- Inflammation
- Obesity
- Insulin resistance
- Metabolic Syndrome X
- Cardiovascular Diseases
- Diabetes Mellitus
- Type 2