Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hiden, U; Lang, U; Desoye, G.
Fetoplacental disturbances in gestational diabetes mellitus.
Gynakol Geburtshilfliche Rundsch. 2009; 49(4): 224-229.
Doi: 10.1159/000301073
PubMed
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- Führende Autor*innen der Med Uni Graz
- Hiden Ursula
- Co-Autor*innen der Med Uni Graz
- Desoye Gernot
- Lang Uwe
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- Abstract:
- The placenta is a fetal organ located at the interface between mother and fetus. Therefore, the placenta is susceptible to maternal and fetal derangements. In gestational diabetes, various hormones, growth factors, cytokines and metabolites have altered levels in the maternal, the fetal compartment and the placenta. Prominent determinants of placental and fetal growth and development are insulin and the insulin-like growth factors (IGF) 1 and 2. Their levels in the maternal and/or fetal circulation are altered resulting from gestational diabetes. This article will describe placental changes in gestational diabetes and discuss the role of insulin, IGF1 and IGF2 therein.
- Find related publications in this database (using NLM MeSH Indexing)
- Birth Weight - physiology
- Diabetes, Gestational - physiopathology
- Female -
- Humans -
- Infant, Newborn -
- Insulin - blood
- Insulin-Like Growth Factor II - metabolism
- Maternal-Fetal Exchange - physiology
- Placental Circulation - physiology
- Pregnancy -