Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Waller, C; Hiller, KH; Pfaff, D; Gattenlohner, S; Ertl, G; Bauer, WR.
Functional mechanisms of myocardial microcirculation in left ventricular hypertrophy: a hypothetical model of capillary remodeling post myocardial infarction.
Microvasc Res. 2008; 75(1):104-111
Doi: 10.1016/j.mvr.2007.04.005
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- Gattenlöhner Stefan
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- OBJECTIVES: Left ventricular (LV) remodeling after myocardial infarction (MI) is characterized by myocyte hypertrophy and a disproportional capillary growth. We developed a hypothetical model of capillary remodeling mechanisms based on quantitative data of microcirculation determined by magnetic resonance (MR) imaging techniques and histology. METHODS: Perfusion and regional capillary blood volume (RBV) were quantified 8 and 16 weeks after MI (mean 27.0+/-2.9% of the left ventricle 16 weeks post MI) or sham operation in rats using MR imaging and were correlated with morphometric data. RESULTS: Maximum perfusion (ml/(g min)) in the remote area decreased from 5.69+/-0.63 to 3.48+/-0.48 compared to sham animals (5.33+/-0.31, p
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Capillaries - pathology Capillaries - physiopathology
- Cell Size -
- Coronary Circulation -
- Disease Models, Animal -
- Female -
- Hypertrophy, Left Ventricular - etiology Hypertrophy, Left Ventricular - metabolism Hypertrophy, Left Ventricular - pathology Hypertrophy, Left Ventricular - physiopathology
- Magnetic Resonance Imaging, Cine -
- Microcirculation -
- Models, Cardiovascular -
- Myocardial Infarction - complications Myocardial Infarction - metabolism Myocardial Infarction - pathology Myocardial Infarction - physiopathology
- Myocytes, Cardiac - pathology
- Oxygen Consumption -
- Rats -
- Rats, Wistar -
- Time Factors -
- Vascular Resistance -
- Ventricular Remodeling -
- Find related publications in this database (Keywords)
- infarction
- remodeling
- capillaries
- regional blood flow
- microcirculation