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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Sandner, A; Helmbold, P; Winkler, M; Gattenlohner, S; Muller-Hermelink, HK; Holzhausen, HJ.
Cutaneous dissemination of nasal NK/T-cell lymphoma in a young girl.
Clin Exp Dermatol. 2008; 33(5):615-618
Doi: 10.1111/j.1365-2230.2008.02777.x
(- Case Report)
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- Co-authors Med Uni Graz
- Gattenlöhner Stefan
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- Abstract:
- In Europe and the USA, the incidence of primary nasal natural killer (NK)/T-cell lymphoma is rare. The skin is one of the predilection sites for dissemination. Cutaneous dissemination is a poor prognostic sign and is consistently fatal. We describe the case of a 17-year-old white German girl with a primary nasal NK/T-cell lymphoma and cutaneous dissemination. She presented with multiple maculopapular patches involving the trunk and thighs, and a 4-week history of headache, fever and fatigue. Biopsies of the skin and the nasal mucosa were taken. Pathological examination of both specimens revealed a NK/T-cell lymphoma. Epstein-Barr virus RNA was detected in the lymphoma cells by in situ hybridization. Unfortunately, the patient died of disease within 1 week.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Diagnosis, Differential -
- Epstein-Barr Virus Infections - immunology Epstein-Barr Virus Infections - pathology
- Fatal Outcome -
- Female -
- Humans -
- Lymphoma, T-Cell - immunology Lymphoma, T-Cell - pathology
- Lymphoma, T-Cell, Cutaneous - immunology Lymphoma, T-Cell, Cutaneous - pathology
- Nose Neoplasms - immunology Nose Neoplasms - pathology
- Skin Neoplasms - pathology